姓名：张建波

研究方向：精神活性物质使用障碍等精神疾病的法医学鉴识及机制与防治研究

教育背景：

2009年9月-2013年7月，河北大学护理学院，本科

2013年9月-2019年3月，西安交通大学法医学院，医学博士

工作经历：

2022年7月至今，副教授，西安交通大学法医学院；

2019年4月-2022年7月，助理教授，西安交通大学法医学院

科研项目（主持）：

1．2022.01-2024.12 肠道拟杆菌通过短链脂肪酸调控甲基苯丙胺渴求的机制研究 （国家自然科学基金青年项目）；

2. 2022.06-2024.12 肠道古氏副拟杆菌通过调控伏隔核缩胆囊素信号参与甲基苯丙胺成瘾的机制 （中央高校基本科研业务费）

3．2021.01-2022.12 伏隔核D1-MSN及其KOR在压力诱导吗啡复吸中的作用机制（陕西省自然科学基金青年项目）；

4．2021.01-2022.12 伏隔核D1中型多棘神经元及其kappa阿片受体在压力诱导吗啡复吸中作用 （陕西省高校科协青年人才托举计划项目）。

学术成果（论文、专著、专利、获奖等）：

[1] Y. Li, Y. Lu, Q. Xie, X. Zeng, R. Zhang, W. Dang, Y. Zhu, J. Zhang, Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder, Psychopharmacology, 239 (2022) 2515-2523.

[2] K. Wang, H. Zhang, J. Ji, R. Zhang, W. Dang, Q. Xie, Y. Zhu, J. Zhang, Expression Quantitative Trait Locus rs6356 Is Associated with Susceptibility to Heroin Addiction by Potentially Influencing TH Gene Expression in the Hippocampus and Nucleus Accumbens, Journal of molecular neuroscience : MN, 72 (2022) 1108-1115.

[3] J. Zhang, X. Fu, Y. Lu, C. Cheng, K. Wang, Y. Zhu, Q. Xie, Hypermethylation in the promoter region of the ADRA1A gene is associated with opioid use disorder in Han Chinese, Brain research, 1793 (2022) 148050.

[4] J. Zhang, C. Deji(#), J. Fan, L. Chang, X. Miao, Y. Xiao, Y. Zhu, S. Li, Differential alteration in gut microbiome profiles during acquisition, extinction and reinstatement of morphine-induced CPP, Progress in neuro-psychopharmacology & biological psychiatry, 104 (2021) 110058.

[5] J. Zhang, Y. Fan, J. Zhou, T. Ma, K. Gao, M. Xu, Y. Xiao, Y. Zhu, Methylation quantitative trait locus rs5326 is associated with susceptibility and effective dosage of methadone maintenance treatment for heroin use disorder, Psychopharmacology, 238 (2021) 3511-3518.

[6] J. Zhang, P. Yan, Y. Li, X. Cai, Z. Yang, X. Miao, B. Chen, S. Li, W. Dang, W. Jia, Y. Zhu, A 35.8 kilobases haplotype spanning ANKK1 and DRD2 is associated with heroin dependence in Han Chinese males, Brain research, 1688 (2018) 54-64.

[7] J. Zhang, N. Wang, B. Chen, Y. Wang, J. He, X. Cai, H. Zhang, S. Wei, S. Li, Blockade of Cannabinoid CB1 receptor attenuates the acquisition of morphine-induced conditioned place preference along with a downregulation of ERK, CREB phosphorylation, and BDNF expression in the nucleus accumbens and hippocampus, Neuroscience letters, 630 (2016) 70-76.

[8] Y. Wang, J. Zhang(#), C. Deji, J. Fan, X. Miao, S. Li, X. Zeng, F. Guan, Differential perturbations of gut microbial profiles and co-occurrence networks among phases of methamphetamine-induced conditioned place preference, Journal of neuroscience research, 99 (2021) 2860-2873.

联系方式：

邮箱：jianbozh@xjtu.edu.cn

电话：029-82655473