姓名：张宝

研究方向：（1）法医物证 （2） 复杂疾病基因组变异解析 

教育背景：

 2010.3-2011.3，美国威斯康辛麦迪逊，访学
2008.9-2011.12，西北农林科技大学，遗传学博士
2005.9-2008.7，西北农林科技大学，遗传学硕士
2001.9-2005.7，西北农林科技大学，动物科学本科

工作经历：

2016.1-至今，西安交通大学医学部法医学院，副教授

2016.9-2017.9， 美国佐治亚理工学院基因组整合中心，访学
2011.12-2015.12， 西安交通大学医学部法医学院，讲师

讲授课程：

本科生《法医物证学》、《法医学》、《刑事科学技术》

研究生《分子遗传学》、《AMER》

科研项目（主持、参与）：

主持陕西省自然科学基金项目（项目编号: 2017JQ8010）在研

主持中国博士后面上项目（项目编号: 2019M663745）在研

主持陕西省卫生健康科研基金项目（项目编号: 2018A010）在研

主持西安交通大学交叉合作项目（项目编号: xjj2017135) 在研

主持国家自然科学基金青年基金项目（项目编号: 31301949）结题

主持中国博士后面上项目 （项目编号: 2013M532056）结题

主持陕西省博士后面上项目 结题

主持重点实验室青年学术骨干培植项目 结题

主持西安交通大学基本科研业务费（项目编号: xjj2013052）结题 

主持西安交通大学新讲师科研启动计划 结题

学术成果（论文、专著、专利、获奖等）：

[1] Ma P, Chen P, Gao J, H Guo, S Li, J Yang, J Lai, X Yang, B Zhang, Y He. Association of MICA gene polymorphisms with thionamide-induced agranulocytosis [published online ahead of print, 2020 Jun 9]. J Endocrinol Invest. 2020;10.1007/s40618-020-01319-0. doi:10.1007/s40618-020-01319-0 (通讯作者)

[2] Jun-Lin Liu, Shao-Qing Li, Feng Zhu, Yu-Xiang Zhang, Ya-Nan Wu, Jing-Si Yang, Bao Zhang, Chun-Xia Yan. Tyrosine Hydroxylase Gene Polymorphisms Contribute to Opioid Dependence and Addiction by Afecting Promoter Region Function. Neuromolecular Med. 2020 Mar 31. doi: 10.1007/s12017-020-08597-0. (通讯作者)

[3] Jia-Yang Gao, Pan Ma, Ying Li, Chun-Xia Yan, Qian Zhang, Xi-Xi Yang, Qiang Shi, Bao Zhang, Xiao-Peng Wen. Association between a TCF4 Polymorphism and Susceptibility to Schizophrenia. Biomed Res Int. 2020 Mar 20;2020:1216303. (通讯作者)

[4] Jiayang Gao, Xiaoyue Song, Hui Wu, Qi Tang, Zhenyu Wei, Xinyu Wang, Xianyong Lan, Bao Zhang. Detection of rs665862918 (15-bp Indel) of the HIAT1 Gene and Its Strong Genetic Effects on Growth Traits in Goats. Animals (Basel). 2020 Feb 23;10(2):358. doi: 10.3390/ani10020358. (通讯作者)

[5] He YY, Hasan AME, Zhang Q, Li SQ, Yang JS, Yan CX, Chen P, Liu Y, Nadeem A, Zhang B. Novel Association between Flavin-Containing Monooxygenase 3 Gene Polymorphism and Antithyroid Drug-Induced Agranulocytosis in the Han Population. Ann Nutr Metab. 2019;74(3):200-206. doi: 10.1159/000497314. Epub 2019 Feb 27.  (SCI, IF=3.051) (通讯作者)

[6] Qiaoli Xie, Hongbo Zhang, Fei Yan, Chunxia Yan, Shuguang Wei, Jianghua Lai, Yunpeng Wang, and Bao Zhang. Morphology and Molecular Identification of Twelve Commercial Varieties of Kiwifruit. Molecules. 2019 Mar 3;24(5). pii: E888. doi: 10.3390/molecules24050888.  (SCI, IF=3.060) (通讯作者)

[7] Zhang B, Chang L, Lan YX, Asif N, Guan FL, Fu KD, Li B, Yan XC, Zhang BH, Zhang YX, Huang ZY, Chen H, Yu J, Li BS. Genome-wide definition of selective sweeps reveals molecular evidence of trait-driven domestication among elite goat (Capra species) breeds for the production of dairy, cashmere, and meat. Gigascience. 2018 Aug 27. (SCI, IF=7.267)

[8] He Y, Zheng J, Zhang Q, Hou P, Zhu F, Yang J, Li W, Chen P, Liu S, Zhang B, Shi B. Association of HLA-B and HLA-DRB1polymorphism with antithyroid drug-inducedagranulocytosis in a Han population from northern China. Sci Rep. 2017 Sep 20;7(1):11950. (SCI, IF=4.259)（通讯作者）

[9] Zhang H, Xie Z, Yang Y, Zhao Y, Zhang B. The Correlation-Base-Selection Algorithm for Diagnostic Schizophrenia Based on Blood-Based Gene Expression Signatures. Biomed Res Int. 2017;2017:7860506. (SCI, IF=2.538)（通讯作者）

[10] Zhang B, Guan F, Chen G, Lin H, Zhang T, Feng J, Li L, Fu D. Common variants in SLC1A2 and schizophrenia: Association and cognitive function in patients with schizophrenia and healthy individuals. Schizophr Res. 2015 Oct 9. pii: S0920-9964(15)30012-8.  (SCI, IF=3.958)

[11] Zhang B, Li DX, Lu N, Fan QR, Li WH, Feng ZF. Lack of Association between the TSPAN18 Gene and Schizophrenia Based on New Data from Han Chinese and a Meta-Analysis. Int J Mol Sci. 2015 May 26;16(6):11864-72.  (SCI, IF=3.687)

[12] Zhang B,  Fan QR, Li WH, Lu N, Fu DK, Kang YJ, Wang N, Li T, Wen XP, Li DX. Association of the NOTCH4 Gene Polymorphism rs204993 with Schizophrenia in the Chinese Han Population. BioMed Research International. 2015. 2015:408096. (SCI, IF=2.538)

[13] Zhang B, Gao CY, Zhang HB, Yang B, Yin JF, Wei SG, Zhu YS, Jia XN, Li SB. Association of the VRK2 gene rs3732136 polymorphism with schizophrenia in a Northwest Chinese Han population. Genet Mol Res. 2015 Aug 14;14(3):9404-11.  (SCI, IF=0.764)

[14] Zhang B, Xu YH, Wei SG, Zhang HB, Fu DK, Feng ZF, Guan FL, Zhu YS, Li SB. Association study identifying a new susceptibility gene (AUTS2) for schizophrenia. Int J Mol Sci. 2014 Oct 24;15(11):19406-16. (SCI, IF=3.687)

[15] Liu R, Wang T, Zhang B, Qin L, Wu C, Li Q, Ma L. Lutein and zeaxanthin supplementation and association with visual function in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2014 Dec 16;56(1):252-8. (SCI, IF=3.388) （共同第一作者）

[16] Zhang B, Guo YK, Li S, Zhang LZ, Lan XY, Hu SR, Chen H. Genotype and haplotypeanalysis of the AZGP1 gene in cattle. Mol Biol Rep. 2012 Dec;39(12):10475-9. (SCI, IF=1.889)

[17] Zhang B, Peñagaricano F, Chen H, Khatib H. Novel transcripts and alternativelyspliced genes are associated with early development in bovine embryos. Animal. 2012 Aug;6(8):1199-205. (SCI, IF=1.870)

[18] Zhang B, Zhao G, Lan X, Lei C, Zhang C, Chen H. Polymorphism in GHRH gene and  its association with growth traits in Chinese native cattle. Res Vet Sci. 2012 Apr;92(2):243-6. (SCI, IF=1.616)

[19] Zhang B, Peñagaricano F, Driver A, Chen H, Khatib H. Differential expression of heat shock protein genes and their splice variants in bovine preimplantation embryos. J Dairy Sci. 2011 Aug;94(8):4174-82. (SCI, IF=2.749)

[20] Zhang B, Zhang Y, Zhang L, Wang J, Li Z, Chen H. Allelic polymorphism detected in the bovine FTO gene. Mol Biotechnol. 2011 Nov;49(3):257-62. (SCI, IF=1.815)

[21] Zhang B, Chen H, Guo Y, Zhang L, Zhao M, Lan X, Zhang C, Pan C, Hu S, Wang J, Lei C. Associations of polymorphism within the GHSR gene with growth traits in Nanyang cattle. Mol Biol Rep. 2009 Nov;36(8):2259-63. (SCI, IF=1.815)

[22] Zhang B, Chen H, Hua L, Zhang C, Kang X, Wang X, Pan C, Lan X, Lei C. NovelSNPs of the mtDNA ND5 gene and their associations with several growth traits in the Nanyang cattle breed. Biochem Genet. 2008 Jun;46(5-6):362-8. (SCI, IF=1.927)

[23] 张宝, 刑博, 魏曙光, 贾小妮, 张洪波, 李生斌. 多巴胺D1、D3受体敲除及双基因敲除对小鼠体重的影响[J]. 中国比较医学杂志, 2014,10:54-57.  

[24]  赵娟, 韩程成, 虞荣斌, 刘蓉, 张宝. 西安市高校学生肌肉疲劳现状及相关因素分析[J]. 中国公共卫生, 2015, 05:638-641.（通讯作者）

[25]   张宝, 魏曙光, 范乾瑞, 李文浩, 李生斌. DRD1基因敲除小鼠繁殖模式分析及鉴定[J]. 家畜生态学报, 2015, 36(10):12-15.

联系方式：

Email: zhangbao_814@mail.xjtu.edu.cn    

电话：029-82655473
联系地址: 西安市雁塔西路76号 西安交通大学医学部法医学院