姓名：陈腾
研究方向：1.法医临床与人类学 2.毒品依赖的机制及防治
教育背景：
(1) 1999-09 至 2002-12, 西安交通大学, 法医学, 博士
(2) 1992-09 至 1995-07, 西安医科大学, 法医学, 硕士
(3) 1985-09 至 1990-07, 西安医科大学, 法医学, 学士
工作经历：
(1) 2007-09 至 今, 西安交通大学, 法医学院, 教授
(2) 2002-08 至 2007-08, 西安交通大学, 医学院法医系, 副教授
(3) 1990-07 至 2002-09, 西安交通大学, 医学院法医系, 讲师
讲授课程：
本科生《法医临床学与人类学》、《法医专业实习》
研究生《基因组学》、《Death Education and Bioethics》
科研项目（主持、参与）：
主持：
(1) 2022-01-01至今, RNA m6A修饰在甲基苯丙胺成瘾中的调控作用及机制研究（国家自然科学基金面上项目 82171879）
(2) 2018-01-01 至 2021-12-31青春期甲基苯丙胺暴露对小鼠脑发育的影响以及作用机制研究（国家自然科学基金面上项目 81772034）
(3) 2015-01-01至2019-12-31 伏隔核miR-29/Dnmt3/Meg3通路参与甲基苯丙胺成瘾的机制研究（国家自然科学基金重点项目 81430048）
(4) 2012-01-01至2015-12-31 METH成瘾小鼠大脑差异表达microRNA及其调控作用研究（国家自然科学基金面上项目 81172913）
(5) 2010-01-01至2012-12-31 METH诱导的小鼠神经元可塑性改变及D3R调控作用的研究（国家自然科学基金面上项目 30973365）
(6) 2006-01-01至2008-12-31 DA受体基因敲除小鼠c-Fos及△fosB的表达与调控 （国家自然科学基金面上项目 30572089)
(7) 2009-01-01至2011-12-31 延胡索乙素对甲基苯丙胺依赖的治疗作用研究（科技部国际合作与交流重点项目 2009DFA31080）
参与：
(1) 2018-01-01 至 2021-12-31基于基因组遗传信息网络的甲基苯丙胺诱导精神障碍关键易感基因的筛选及其作用机制研究 （国家自然科学基金面上项目 81772033）
学术成果（论文、专著、专利、获奖等）：
发表论文
1. Tong Ni, Li Zhu, Shuai Wang, Weili Zhu, Yanxue Xue, Yingjie Zhu, Dongliang Ma, Hongyan Wang, Fanglin Guan*, Teng Chen*. Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression. Molecular Psychiatry, 2022. https://doi.org/10.1038/s41380-022-01662-z.
2. Li Zhu, Feifei Wu, Zhilan Yan, Lijun He, Shufei Wang, Haohao Hu, Eyleen L. K. Goh, Yingjie Zhu, Fanglin Guan* , Teng Chen*. A novel microRNA, novel-m009C, regulates methamphetamine rewarding effects. Molecular Psychiatry, 2022. https://doi.org/10.1038/s41380-022-01651-2.
3. Min Liang, Li Zhu, Rui Wang, Hang Su, Dongliang Ma, Hongyan Wang, Teng Chen*. Methamphetamine Exposure in Adolescent Impairs Memory of Mice in Adulthood Accompanied by Changes in Neuroplasticity in the Dorsal Hippocampus. Front Cell Neurosci. 2022,16:892757.
4. Shuai Wang, Ming Li, Linlan Su, Wang Yu, Dongliang Ma D, Hongyan Wang, Jie Zhu, Teng Chen*. Knockout of Dopamine D3 Receptor Gene Blocked Methamphetamine-Induced Distinct Changes of Dopaminergic and Glutamatergic Synapse in the Nucleus Accumbens Shell of Mice. Front Cell Neurosci. 2022 May 30;16:893190.
5. Dan Liu, Min Liang, Li Zhu, Ting-ting Zhou, Yu Wang, Rui Wang, Fei-fei Wu, Eyleen L. K. Goh*, Teng Chen*. Potential Ago2/miR-3068-5p Cascades in the Nucleus Accumbens Contribute to Methamphetamine-Induced Locomotor Sensitization of Mice. Frontiers in Pharmacology. 2021, 12: 708034.
6. Jiaqi Li, Li Zhu, Hang Su, Dan Liu, Zhilan Yan, Tong Ni, Han Wei Eyleen L.K. Goh*, Teng Chen*. Regulation of miR-128 in the nucleus accumbens affects methamphetamine-induced behavioral sensitization by modulating proteins involved in neuroplasticity. Addiction Biology. 2021, 26: e12881.
7. Guang Chu, Meng-qi Han, Ling-ling Ji, Mu-jia Li, Hong Zhou, Teng Chen⁎, Yu-cheng Guo*, Will different sagittal and vertical skeletal types relate the soft tissue thickness: A study in Chinese female adults. Legal Medicine, 2020, 42: 101633.
8. Yu-cheng Guo, Ya-hui Wang, Andreas Olze, Sven Schmidt, Ronald Schulz, Heidi Pfeiffer, Teng Chen*, Andreas Schmeling, Dental age estimation based on the radiographic visibility of the periodontal ligament in the lower third molars: application of a new stage classification. International Journal of Legal Medicine, 2020 Jan;134(1):369-374.
9. Hang Su, Li Zhu, Jiaqi Li, Rui Wang, Dan Liu, Wei Han, Jean Lud Cadet, Teng Chen∗. Regulation of microRNA-29c in the nucleus accumbens modulates methamphetamine-induced locomotor sensitization in mice. Neuropharmacology, 2019, 148: 160-168.
10. Jiaqi Li, Li Zhu, Fanglin Guan, Zhilan Yan, Dan Liu, Wei Han, Teng Chen*. Relationship between schizophrenia and changes in the expression of the long non-coding RNAs Meg3, Miat, Neat1 and Neat2. Journal of Psychiatric Research, 2018, 106: 22-30.
11. Nan Dong, Jie Zhu, Wei Han, Shuai Wang, Zhilan Yan, Dongliang Ma, Eyleen L.K. Goh, Teng Chen*. Maternal methamphetamine exposure causes cognitive impairment and alteration of neurodevelopment-related genes in adult offspring mice. Neuropharmacology, 2018,140, 25-34.
12. Liu D, Zhu L, Ni T, Guan FL, Chen YJ, Ma DL, Goh ELK, Chen T*. Ago2 and Dicer1 are involved in METH-induced locomotor sensitization in mice via biogenesis of miRNA. Addiction Biology. 2018, 24, 498-508.
13. Cao G, Zhang Y, Zhu L, Zhu J, Zhao N, Dong N, Dang Y, Chen Y, Chen T*. The inhibitory effect of levo-tetrahydropalmatine on the methamphetamine-induced spatial memory impairment in mice. Neuroscience Letters. 2018, 672: 34-39.
14. Yanjiong Chen, Cuo Yang, Li Zhu, Jiaqi Li, Fanglin Guan, Teng Chen*. Depletion of D3 dopamine receptor affects methamphetamine-induced expression patterns of Pde4b and Atf3. Neuroscience Letters. 2018, 665: 54-60.
15. Xia Li, Feng Wu, Li Xue, Biao Wang, Juping Li, Yanjiong Chen, Teng Chen*. Methamphetamine causes neurotoxicity by promoting polarization of macrophages and inflammatory response. Human & Experimental Toxicology. 2018, 37(5): 486-495.
16. Guo YC, Chu G, Olze A, Schmidt S, Schulz R, Ottow C, Pfeiffer H, Chen T*, Schmeling A. Application of age assessment based on the radiographic visibility of the root pulp of lower third molars in a northern Chinese population. International Journal of Legal Medicine, 2018, 132: 825-829.
17. Yu-cheng Guo, Guang Chu, Andreas Olze, Sven Schmidt, Ronald Schulz, Christian Ottow, Heidi Pfeiffer, Teng Chen*, Andreas Schmeling. Age estimation of Chinese children based on second molar maturity. International Journal of Legal Medicine, 2018, 132: 807-813.
18. Yu-cheng Guo, Mu-jia Li, Andreas Olze, Sven Schmidt, Ronald Schulz, Hong Zhou, Heidi Pfeiffer, Teng Chen*, Andreas Schmeling. Studies on the radiographic visibility of the periodontal ligament in lower third molars: can the Olze method be used in the Chinese population? International Journal of Legal Medicine, 2018, 132: 617-622.
19. Ju-ping Li#, Peng Liu#, Gang Lei, Zheng Chu, Fei Liu, Chao-feng Shi, Yong-hui Dang*, Teng Chen*. The Role of HINT1 in Methamphetamine-Induced Conditioned Place Preference. Neurotoxicity Research, 2018, 33:353-361.
20. Zhu J, Zhao N, Chen Y, Zhu L, Zhong Q, Liu J, Chen T*. Sodium butyrate modulates a methamphetamine-induced conditioned place preference. J Neurosci Res. 2017, 95(4):1044-1052.
21. Zhu L, Li J, Dong N, Guan F, Liu Y, Ma D, Goh EL, Chen T*. mRNA changes in nucleus accumbens related to methamphetamine addiction in mice. Sci Rep. 2016, 6:36993.
22. Zhu L#, Zhu J#, Liu Y, Chen Y, Li Y, Chen S, Li T, Dang Y, Chen T*. Chronic Methamphetamine Regulates the Expression of MicroRNAs and Putative Target Genes in the Nucleus Accumbens of Mice. J Neurosci Res, 2015, 93(10):1600-1610.
23. Zhu L#, Zhu J#, Liu Y, Chen Y, Li Y, Huang L, Chen S, Li T, Dang Y, Chen T*. Methamphetamine induces alterations in the long non-coding RNAs expression profile in the nucleus accumbens of the mouse. BMC Neurosci, 2015, 16:18.
24. Xue L, Li X, Ren HX, Wu F, Li M, Wang B, Chen FY, Cheng WY, Li JP, Chen YJ*, Chen T*. The dopamine D3 receptor regulates the effects of Methamphetamine on LPS-induced cytokine production in murine mast cells. Immunobiology, 2015, 220(6):744-752. IF：2.7809
25. Yu-cheng Guo, Chun-xia Yan*, Xing-wei Lin, Hong Zhou, Ju-ping Li, Feng Pan, Zhi-yong Zhang, Lai Wei, Zheng Tang, Teng Chen*. Age estimation in northern Chinese children by measurement of open apices in tooth roots. Int J Legal Med, 2015, 129(1): 179-186. IF: 2.8619
26. Yu-cheng Guo, Chun-xia Yan*, Xing-wei Lin, Wen-tao Zhang, Hong Zhou, Feng Pan, Lai Wei, Zheng Tang, Feng Liang, Teng Chen*. The influence of impaction to the third molar mineralization in northwestern Chinese population. Int J Legal Med, 2014, 128(4): 659-665. IF: 2.7139
27. Yu-cheng Guo, Chun-xia Yan*, Xing-wei Lin, Hong Zhou, Feng Pan, Lai Wei, Zheng Tang, Feng Liang, Teng Chen*. Studies of the chronological course of third molars eruption in a northern Chinese population. Arch Oral Biol, 2014, 59(9): 906-911. IF: 1.735
28. Zhao Na, Chen Yanjiong, Zhu Jie, Wang Liang, Cao Guofen, Dang Yonghui, Yan Chunxia, Wang Jiabei, Chen Teng*. Levo-tetrahydropalmatine attenuates the development and expression of methamphetamine-induced locomotor sensitization and the accompanying activation of ERK in the nucleus accumbens and caudate putamen mice. Neuroscience, 258:101-110, 2014.
29. Su Hongliang, Zhu Jie, Chen Yanjiong, Zhao Na, Han Wei, Dang Yonghui, Xu Ming, Chen Teng*. Roles of levo-tetrahydropalmatine in modulating methamphetamine reward behavior. Physiol Behav, 118: 195-200, 2013.
30. Cao Guofen, Zhu Jie, Zhong Qing, Shi Chaofeng, Dang Yonghui, Han Wei, Liu Xinshe, Xu Ming, Chen Teng*. Distinct roles of methamphetamine in modulating spatial memory consolidation, retrieval, reconsolidation and the accompanying changes of ERK and CREB activation in hippocampus and prefrontal cortex. Neuropharmacology, 67: 144-154, 2013.
参编教材
1. 国家卫生健康委员会“十三五”规划教材，全国高等学校教材《法医学》（第七版），副主编（主编王保捷，侯一平）人民卫生出版社，2018年6月。
2. 《法医临床学》副主编（主编刘技辉，第5版）（卫生部“十一五”规划教材，全国高等医药教材建设研究会规划教材），2016年7月。
3. 中国高等教育学会医学教育专业委员会规划教材《法医学》副主编（主编赵虎，王慧君），北京大学医学出版社，2013年12月。
4. 现代实用法医学（西安交通大学出版社），副主编（主编：李生斌），2010年11月。
5. 《法医临床学》（卫生部“十一五”规划教材，人民卫生出版社，第4版），参编（主编刘技辉），2009年7月。
获奖情况
1. 2009年 国家科技进步二等奖, 人类基因组多态性和特殊微量物证个体识别关键技术及应用，排名第3
2. 2007年 陕西省科技进步一等奖，中华民族群体基因组多态性与个体识别基础研究，排名第3
3. 2007年 教育部“新世纪优秀人才支持计划”入选者
4. 2003年 第四届“陕西青年科技奖”
其他：
学术兼职
1. 教育部法医学专业教学指导委员副主任委员
2. 国家卫健委法医学重点实验室副主任
3. 法医学国家重点学科毒品依赖方向学术带头人
4. 中国法医学会法医临床专业委员会副主任委员
5. 陕西省法医学会 理事长
6. 《法医学杂志》、《西安交通大学学报（医学版）》杂志编委
7. 上海市法医学重点实验室学术委员会委员
联系方式：
邮箱：chenteng@xjtu.edu.cn
电话：029-82657977
